Notice: Undefined index: version in /home/ffbwebSite/home/templates/ffb/index.php on line 62
Background
Gray font color on white background Black font color on white background White font color on black background White font color on dark blue background
Font Size
Forgot login?
Login
Funded Grants

FY11 Grants


Center Grant Awards

Berman-Gund Laboratory for the Study of Retinal Degenerations
Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA
Eliot Berson, MD, Center Director


Berson, Eliot MD, Robert Brockhurst, MD, Bernard Rosner, PhD
Module I, Clinical Research Studies of Retinitis Pigmentosa  and  Allied Diseases


Eliot Berson, MD
Module III, Molecular Genetic Studies of Retinitis Pigmentosa and Allied Diseases

Michael A. Sandberg, PhD, Basil S. Pawlyk, M.Sc., Tiansen Li, PhD
Module IV, Therapeutic Studies in Mouse Models of Retinal Degeneration


Children’s Hospital of Philadelphia (CHOP) - Penn Pediatric Center for Retinal Degenerations
University of Pennsylvania, Philadelphia, PA
Bennett, Jean MD, PhD, Center Director


Eric Pierce, MD, PhD
Module I, Clinical Characterization and Treatment of Pediatric Retinal Degenerations

Jean Bennett, MD, PhD
Module II, Development of Gene Therapies for Early Onset Retinal Degenerations

Jessica Morgan, PhD
Module IV, Assessment of Retinal Structure and Function with High Resolution Optical Methods


The Cleveland Clinic Foundation Research Center for the Study of Retinal Degenerative Diseases
The Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, OH
Joe Hollyfield, PhD, Center Director


Joe Hollyfield, PhD, Mary Rayborn, PhD, Karen Shadrach, PhD, John Crabb, PhD
Module I, A New Mouse Model for AMD

John Crabb, PhD, Xianquan Zhan, MD, PhD, Xiarong Gu, PhD, Ellen Simpson, RN, BSN, Ram Nagaraj, Daniel Organiscic
Module II, Proteomics and Biomarkers for AMD

Stephanie Hagstrom, PhD, Gayle Pauer, BS, Ellen Simpson, RN, BSN
Module IV, Genomic Susceptibility Markers for AMD

Neal Peachey, PhD and Jiang Wu, MD
Module V, Electrophysiological Markers for Retinal Disease in the Mouse


Greater New York Regional Research Center for the Study of Retinal Degenerative Diseases
Columbia University, New York, NY
University of Medicine and Dentistry of New Jerse
y, Newark, NJ
Lucian Del Priore, MD, PhD, Center Director


Stephen Tsang, MD, PhD
Module I, Assessing severity, progression, and prognosis of I) ABCA4 retinopathies and II) retinitis pigmentosa (RP)

Marco Zarbin, MD, PhD
Module II, Toxicity assessment of bovine corneal endothelial cell conditioned media following subretinal injection in pigs

Lucian Del Priore, MD and Hui Cai, MD, PhD

Module III, Bruch's Membrane Repair in Advanced AMD: A Regenerative Medicine Approach

Rando Allikmets, PhD
Module IV, Gene Therapy for Stargardt's Disease

Janet Sparrow, PhD
Module V, Assessing Treatment Outcomes in Pre-clinical Studies of ABCA4-related Retinal Disease, Relevance to Patient Studies


Kearn Family Center for the Study of Retinal Degeneration
University of California at San Francisco
University of California, Berkeley, Sacramento, CA
Stanford School of Medicine, Stanford, CA
Loyola Marymount University, Los Angeles, CA
LaVail, Matthew PhD, Center Director


Matthew LaVail, PhD
Module I, Neuroprotective and Gene-Based Therapies for Retinal Degenerations

John Flannery, PhD
Module II, Viral-Mediated Gene Therapy for Retinal Degenerations

Douglas Vollrath, MD, PhD
Module III, Identification of Proteins Required for Endogenous Neuroprotection and Retinal Pigment Epithelium (RPE) Phagocytosis

Jacque Duncan, MD and Austin Roorda, PhD
Module IV, High Resolution Retinal Imaging in Patients with Inherited Retinal Degenerations


Oregon Health and Science University Research Center for the Study of Retinal Degenerations
Oregon Health and Science University, Portland, OR
University of Florida College of Medicine, Gainesville, FL
Richard Weleber, MD, Center Director


Richard Weleber, MD, Peter Francis, MD, PhD, Chris Johnson, PhD

Module I, Clinical and Human Studies (Core Module), Module I Supplement:  Study of Autoimmune Retinopathies

Martha Neuringer, PhD, Brett Jeffrey, PhD, William Hauswirth, PhD, Betsy Ferguson, PhD, Richard Weleber, MD
Module III, Nonhuman Primate Models of Retinal Disease

William Hauswirth, PhD

Module V, Cone Targeted Gene Therapy


Paris Research Center for the Study of Retinal Degenerative Diseases
Inserm, Institut de la Vision, Paris, France
Jose-Alain Sahel, MD, Center Director


Thierry Léveillard, PhD
Module I, Molecular Signaling of Cone Rescue and Rod Differentiation

Christine Petit, MD

Module III, Usher I Syndrome Pathogenesis

Saddek Mohand-Said, MD, PhD
Module IV, Optimization and Development of Morphological and Functional Retinal Exploration Techniques of Age-related and Inherited Retinal Degeneration Cohort Follow-up and Clinical Studies


PENN Large Animal Model Translational and Research Center
University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA
Cornell University, Ithaca, NY
Gustavo Aguirre, VMD, PhD, PhD, Center Director


Gregory Acland, BVSc, Gustavo Aguirre, VMD, PhD, William Beltran, VMD, PhD, Andras Komaromy, DVM, PhD
Module 1, Medical Therapy Service

Gustavo Aguirre, VMD, PhD, Barbara Zangerl, VMD, PhD, William Beltran, VMD., PhD
Module II, Identification, Development and Molecular/Cellular Studies of New and Established Canine Retinal Degeneration Models

Barbara Zangerl, VMD, PhD and Gustavo Aguirre, VMD, PhD
Module III, Gene Expression/Molecular Pathways in Photoreceptor Cell Death/Survival


Research Center for Macular Degeneration and Allied Retinal Diseases
University of Iowa, Iowa City, IA
Edwin Stone, MD, PhD, Center Director


Edwin Stone, MD, PhD, Val Sheffield, MD, PhD, Terry Braun, PhD, James Folk, MD, Steve Russell, MD, Becky Johnston, Dianna Brack
Module I, Large Scale Collaborative Genotype/Phenotype Correlations

Val Sheffield, MD, PhD, Terry Braun, PhD, Edwin Stone, MD, PhD, Joseph Janutka, Jade East
Module II, Discovery of New Retinal Disease Genes

Robert Mullins, PhD, Diane Slusarski, PhD, Val Sheffield, MD, PhD, Edwin Stone, MD, PhD, Beverly Davidson, PhD, Markus Kuehn, PhD, Alisdair Philp, PhD, Marissa Olvera
Module III, Gene Transfer and Animal Models

Thomas Casavant, PhD, Todd Scheetz, PhD, Jian Huang, PhD, Kai Wang, PhD, Edwin Stone, MD, PhD, Val Sheffield, MD, PhD,  Maureen Megonigal, PhD
Module V, Regulatory Elements and Modifier Genes in Human Retinal Degeneration


Research Center for the Study of Retinal Degenerative Diseases at the Institute of Ophthalmology and Moorfields Eye Hospital
Institute of Ophthalmology and Moorfields Eye Hospital London, University College London, England, United Kingdom
Frederick Fitzke, PhD, Center Director


Frederick Fitzke, PhD, AT Moore, PhD, Alan Bird, PhD, Andrew Webster, MD, Michel Michaelides, MD, Graham Holder, PhD, Anthony Robson, MD, John Yates, PhD
Module II, Imaging and Psychophysical Studies in Retinal Degenerations

Shomi Bhattacharya, PhD, Christina Chakarova
Module IV, Genetic Studies and Functional Genomics of Retinal Diseases


Scheie Eye Institute Retinal Degeneration Center
University of Pennsylvania School of Medicine, Scheie Eye Institute, Philadelphia, PA
University of Florida College of Medicine, Gainesville, FL
Samuel Jacobson, MD, PhD, Center Director


Samuel Jacobson, MD, PhD
Module I, FFB Center Grant Clinical Module

Artur Cideciyan, PhD
Module II, Translational Studies

William Hauswirth, PhD
Module III, Gene Therapy for Dominant Stargardt's Disease, GC1 LCA and CEP290 LCA

Krzysztof Palczewski, PhD

Module IV, Pharmacological Therapy for Retinal Degenerations

Gustavo Aguirre, VMD, PhD, PhD and William Beltran, DVM, PhD
Module V, Characterization of Retinal Remodeling in Canine Models of LCA/ Early Onset Retinal Degeneration


Southwest Regional Center for the Study of Retinal Degenerative Diseases
Retina Foundation of the Southwest, Dallas, TX
University of Texas, Houston, TX
University of Oklahoma, Oklahoma City, OK
Robert Anderson, MD, PhD and David Birch, PhD, Center Directors


David Birch, PhD, Rand Spencer MD, Dianna Wheaton, MS, Dennis Hoffman PhD
Module I, Treatment Trials for Retinal Degenerative Diseases

Dianna Wheaton, MS, David Birch, PhD, Stephen Daiger, PhD

Module II, Southwest Eye Registry

Stephen Daiger, PhD, Lori Sullivan, PhD, Sara Bowne, PhD
Module V, Molecular Studies of Autosomal Forms of RP

Stephen Daiger, PhD
Module VI, “RetNet”

Robert Anderson, MD, PhD
Module VII, Biochemical Studies of the Function of the ELOVL4 Protein

James McGinnis, PhD
Module VIII, Vacancy Engineered Inorganic Particles and the Prevention of Retinal Degeneration

Muayyad Al-Ubaidi, PhD
Module IX, Role of Tyrosylprotein Sulfotransferase (TPST-1) in rod and cone associated disorders

Muna Naash, PhD
Module X, Delivery and Targeting of Ocular Therapeutics using Nanotechnology


University of Illinois at Chicago Research Center for the Study of Retinal Degenerative Diseases
University of Illinois, Eye and Ear Infirmary, Chicago, IL
Gerald Fishman, MD, Center Director


Gerald Fishman, MD, Kenneth Alexander, PhD, Robert Anderson, PhD, Janet Szlyk, PhD, Marty Lindeman, Martha Apushkin, PhD
Module I, Clinical Investigations

Gerald Fishman, MD, Edwin Stone, MD, PhD, Robert Koenekoop, MD, PhD, William Kimberling, PhD
Module II, Collaborative Molecular Genetic Studies


Wilmer Eye Institute Research Center for the Study of Retinal Degenerative Diseases
Johns Hopkins University School of Medicine, Baltimore, MD
Duke University, Durham, NC
Peter Campochiaro, MD, Center Director


Nicholas Katsanis, PhD
Module I, Identification of Genetic Defects in Patients with AMD

Jeremy Nathans, MD, PhD and Amir Rattner, PhD

Module III, The Retinal Stress Response, Mueller Glia, and Stress-Induced Photoreceptor Neuroprotection

Nicholas Marsh-Armstrong, PhD
Module IV, Inhibiting Photoreceptor Degeneration in Transgenic Xenopus Reporter Lines

Jennifer Sung, MD, Peter Campochiaro, MD, Solomon Snyder, MD
Module V, Protection of Photoreceptors from Oxidative Damage by Heme Oxygenase, Bilirubin, and Biliverdin Reductase

Donald Zack, MD, PhD
Module VI, Rescue of Neurotrophic Factors:  Identification and Molecular Characterization of Upregulated Genes

Peter Campochiaro, MD
Module VIII, Effect of Sustained Expression of Neurotrophic Factors and Molecular Chaperones on Retinal Degenerations


W.K. Kellogg Eye Center for the Study of Retinal Degenerative Diseases
University of Michigan, W.K. Kellogg Eye Center, Ann Arbor, MI
University of Massachusetts Medical School
University of California at San Diego
John Heckenlively, MD, Center Director


John Heckenlively, MD

Module I, Human Clinical Studies of Retinal and Macular Degenerative Diseases

Radha Ayyagari, PhD
Module II, Molecular Genetic Analysis of Patients with Retinitis Pigmentosa and Macular Degeneration

Hemant Khanna, PhD
Module IV, Molecular Mechanisms of Pathogenesis of X-linked Retinal dystrophies

Debra Thompson, PhD

Module V, Therapeutic Intervention in Vitamin A Metabolism in Visual Cycle and Related Defects

David Zacks, MD, PhD

Module VI, Autophagy and control of photoreceptor cell death in hereditary retinal degeneration


Back to top

Research Facilities

Joe Hollyfield, PhD
The Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, OH

Pathophysiology Facility for the Study of Retinal Degenerative Diseases

Back to top

Individual Grants

Cellular and Molecular Mechanisms of Disease

Wolfgang Baehr, PhD
University of Utah, Moran Eye Center, Salt Lake City, UT

Animal Models of Retinal Degeneration

Lizbeth Hedstrom, PhD
Brandeis University, Waltham, MA

Transgenic Mouse Models of RP10 Retinitis Pigmentosa

David Krizaj, PhD
University of Utah, Moran Eye Center, Salt Lake City, UT

Calcium Overload in Retinitis Pigmentosa Model:  Mechanisms and Treatment Strategies

Yun Le, Z. PhD
University of Oklahoma Health Sciences Center, Oklahoma City, OK

A Mouse Model of Geographic Atrophy

Patsy Nishina, PhD
Jackson Laboratory, Bay Harbor, ME

Molecular Mechanisms Important in Outer Segment Development and Maintenance

Eric Pierce, MD, PhD
University of Pennsylvania School of Medicine, Scheie Eye Institute, Philadelphia, PA

RNA Splicing Factors in Retinitis Pigmentosa

Ronald Roepman, PhD
Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands

Unraveling the Molecular Disease Mechanism of LCA5 and Associated Ciliary Blinding Disorders

Back to top

Clinical: Structure and Function Studies

Michael Gorin, MD, PhD
University of California, Los Angeles

Clinical and Genetic Characterization of Stargardt and Stargardt-like Macular Dystrophies:
The Potential Role of AMD risk factors on the severity and progression of these macular dystrophies

Pierre Lachapelle, PhD
McGill University, Montreal, QC

Extracting Diagnostically Significant Information from the Nearly Extinguished Human Photopic Electroretinogram:  Principle, Methods, and Clinical Significance

Gene Therapy

Alberto Auricchio, MD
TIGEM, Naples, Italy

Use of Erythropoeitin Derivatives for Treatment of Retinitis Pigmentosa

Maria Gorbatyuk, PhD
University of Florida College of Medicine, Gainesville, FL

Gene Therapy for Autosomal Dominant Retinitis Pigmentosa Based on the Overexpression of Molecular Chaperone GRP78

Robert Molday, PhD
University of British Columbia, Vancouver, BC

Gene Therapy for X-linked Juvenile Retinoschisis

Miguel Seabra, MD, PhD
Imperial College of London, London, UK

Novel Therapy Studies in Mouse Models of Choroideremia

Uwe Wolfrum, PhD
Johannes Gutenberg University of Mainz, Mainz, Germany

Gene Therapeutic Strategies for the Usher Syndrome USH1C in the Retina

Jun Yang, PhD
University of Utah, Moran Eye Center, Salt Lake City, UT

Gene Therapy for Retinitis Pigmentosa in Usher Syndrome Type 2

Back to top

Genetics

Stephen Daiger, PhD
University of Texas, Houston, TX
Factors Affecting Clinical Consequences of Mutations Causing X-Linked Retinitis Pigmentosa
Anneke den Hollander, PhD
Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands
Finding New Genes for arRP and LCA Using Next-Generation Sequencing

Albert Edwards, MD, PhD
Oregon University, Eugene, OR
Molecular Genetics of Macular Degeneration

Qin Liu, PhD
University of Pennsylvania School of Medicine, Scheie Eye Institute, Philadelphia, PA
Novel Candidate Disease Genes and Inherited Retinal Degenerations

Dror Sharon, PhD
Hadassah-Hebrew University Medical Center, Jerusalem, Israel
Identification of Characterization of Novel Retinal Degeneration Genes Using Autozygosity Mapping

Novel Medical Therapy

John Ash, PhD
University of Oklahoma, Oklahoma City, OK

Neuroprotection by Leukemia Inhibitory Factor

Nicolas Bazan, MD, PhD
LSU Health Sciences Center, New Orleans, LA

Neuroprotectin D1 Slows Photoreceptor Degeneration

John Flannery, PhD
University of California at Berkeley

Transfer of Light Activated Ion Channels to Retinal Ganglion Cells

Regenerative Medicine

Constance Cepko, PhD   
Harvard Medical School, Boston, MA

Production of Photoreceptor Cells by Mueller Glia

Sarah Tao, PhD
Charles Stark Draper Laboratory, Cambridge, MA

Nanostructured Thin Films for Retinal Regeneration

David N Zacks, MD, PhD
University of Michigan, W.K. Kellogg Eye Center, Ann Arbor, MI

Transplantation of Photoreceptor Precursors

Back to top

Career Development Awards

Peter Francis, MD, PhD
Oregon Health and Science University, Portland, OR

Gene Therapy for Retinal Degeneration

Michael Grassi, MD, PhD
University of Chicago Medical Center, Chicago, IL

Cellular Studies of Apoptosis in RP using Small Molecule Screening and RNA Interference

Mark Pennesi, MD, PhD
Oregon Health and Science University, Portland, OR

Electrophysiological Analysis of Neuronal Modulators for Retinal Degenerations
David Telander, MD, PhD
University of California, Davis, Sacramento, CA
Immune Regulation of Retinal Stem Cell Migration and Survival

Stephen Tsang, MD, PhD
Columbia University, New York, NY

Stem Cell Therapy for Early Onset Retinal Dystrophy in an Animal Model

WOMAN’S CAREER DEVELOPMENT AWARDS

Isabelle Audo, MD, PhD
CHNO des Quatre-Vingts, Paris, France

Phenotype/Genotype Correlation in Inherited Retinal Dystrophies of the French Population

Arlene Drack, MD
University of Iowa, Iowa City, IA

Gene Replacement Therapy of Bardet-Biedl Syndrome

Ruifang Sui, MD, PhD
Peking Union Medical College Hospital, Beijing, China

Clinical and Genetic Research of Inherited Ocular Diseases in China

Back to top

 

WYNN-GUND TRANSLATIONAL RESEARCH ACCELERATION PROGRAM AWARDS

Clinical Studies

Birch, David PhD
Foundation of the Southwest
Infrastructural Support for Clinical Trials at Retina Foundation of the Southwest Retina
Gerald Fishman, MD
University of Illinois, Eye and Ear Infirmary, Chicago, IL
Autosomal Recessive Retinitis Pigmentosa

Samuel Jacobson, MD, PhD
University of Pennsylvania School of Medicine, Scheie Eye Institute, Philadelphia, PA

Autosomal Recessive Retinitis Pigmentosa

Richard Weleber, MD
Oregon Health and Science University, Portland, OR

Autosomal Recessive Retinitis Pigmentosa

Genetics

Stephen Daiger, PhD
University of Texas, Houston, TX

Targeted High-Throughput Sequencing for Gene Delivery in Retinitis Pigmentosa

Edwin Stone, MD, PhD
University of Iowa, Iowa City, IA

Autosomal Recessive Retinitis Pigmentosa

Gene Therapy

Hauswirth, William, PhD
University of Florida

Retinogeographic Distribution of Secreted Retinoschisin when Delivered by AAV Vectors

Molday, Robert, PhD Vectors
University of British Columbia

Retinogeographic Distribution of Secreted Retinoschisin when Delivered by AAV

Neuringer, Martha, PhD   
Oregon Health & Science University

Retinogeographic Distribution of Secreted Retinoschisin when Delivered by AAV Vectors

Novel Medical Therapies

Craig Beeson, PhD
Mitochem Therapeutics, LLC, Charleston, SC

Infrastructural Support for Studies on High Content Metabolic for Anti-Degenerative Agents in the Retina

Matthew LaVail, PhD
University of California at San Francisco

Neuroprotective Therapy for Retinal Degenerations:  Optimal Photoreceptor Protection, Synergistic Effects and Combinational Approaches

Thierry Léveillard, PhD
Inserm, Institut de la Vision, Paris, France

Identification of Cone Protecting Molecules from Natural Compounds Libraries

Barbel Rohrer, PhD
Medical University of South Carolina, Charleston, SC

High Content Metabolic Screens for Anti-Degenerative Agents in the Retina

Donald Zack, MD, PhD
Johns Hopkins University School of Medicine, Baltimore, MD

Screening for Factors that Promote Photoreceptor Cells' Survival and Differentiation


Preclinical Studies

William Hauswirth, PhD
University of Florida College of Medicine, Gainesville, FL

MYO7A Gene Therapy for Usher 1B

Samuel Jacobson, MD, PhD
University of Pennsylvania School of Medicine, Scheie Eye Institute, Philadelphia, PA

MYO7A Gene Therapy for Usher's Syndrome- SEI

David Williams, PhD
University of California, Los Angeles

MYO7A Gene Therapy for Usher's Syndrome- UCLA

Shalesh Kaushal, MD, PhD
University of Massachusetts Medical School

A Safety and Efficacy Study of Valproic Acid Administration in Recessive Retinitis Pigmentosa Rodent Models

Regenerative Medicine

David Gamm, MD, PhD
University of Wisconsin, Madison, W
I
Customized iPS Cell Therapy for Recessive Monogenetic Retinal Degenerative Disease

Thomas Reh, PhD
University of Washington School of Medicine, Seattle, WA

Human Embryonic Stem Cells Transplantation in Mice and Non-Human Primates

Enhanced Career Development Award

Hendrik Scholl, MD MA
Johns Hopkins University School of Medicine, Baltimore, MD

Structure-Function Correlation in Inherited Retinal Degenerations: Development of Surrogate Endpoints for Clinical Trials

Miscellaneous

Christina Clark
Foundation for Interdisciplinary Motor Neuron Medicine

Scientific Advances in Adaptive Clinical Trials Workshop

Craig Beeson, PhD
Mitochem Therapeutics, LLC

Infrastructural Support for Studies on High Content Metabolic for Anti-Degenerative Agents in the Retina

Back to top

US Images

Chapters

Select a state from the dropdown below to view local chapters.


Free Information

Register here to receive free information about your eye condition and research efforts to find treatments and cures.

Race to Cure Blindness banner
VisionWalk banner
Faces of the Foundation banner
Events Calendar