FY11 Grants
Center Grant Awards
Berman-Gund Laboratory for the Study of Retinal Degenerations Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA Eliot Berson, MD, Center Director Berson, Eliot MD, Robert Brockhurst, MD, Bernard Rosner, PhD Module I, Clinical Research Studies of Retinitis Pigmentosa and Allied Diseases Eliot Berson, MD Module III, Molecular Genetic Studies of Retinitis Pigmentosa and Allied Diseases Michael A. Sandberg, PhD, Basil S. Pawlyk, M.Sc., Tiansen Li, PhD Module IV, Therapeutic Studies in Mouse Models of Retinal Degeneration Children’s Hospital of Philadelphia (CHOP) - Penn Pediatric Center for Retinal Degenerations University of Pennsylvania, Philadelphia, PA Bennett, Jean MD, PhD, Center Director Eric Pierce, MD, PhD Module I, Clinical Characterization and Treatment of Pediatric Retinal Degenerations Jean Bennett, MD, PhD Module II, Development of Gene Therapies for Early Onset Retinal Degenerations Jessica Morgan, PhD Module IV, Assessment of Retinal Structure and Function with High Resolution Optical Methods The Cleveland Clinic Foundation Research Center for the Study of Retinal Degenerative Diseases The Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, OH Joe Hollyfield, PhD, Center Director Joe Hollyfield, PhD, Mary Rayborn, PhD, Karen Shadrach, PhD, John Crabb, PhD Module I, A New Mouse Model for AMD John Crabb, PhD, Xianquan Zhan, MD, PhD, Xiarong Gu, PhD, Ellen Simpson, RN, BSN, Ram Nagaraj, Daniel Organiscic Module II, Proteomics and Biomarkers for AMD Stephanie Hagstrom, PhD, Gayle Pauer, BS, Ellen Simpson, RN, BSN Module IV, Genomic Susceptibility Markers for AMD Neal Peachey, PhD and Jiang Wu, MD Module V, Electrophysiological Markers for Retinal Disease in the Mouse Greater New York Regional Research Center for the Study of Retinal Degenerative Diseases Columbia University, New York, NY University of Medicine and Dentistry of New Jersey, Newark, NJ Lucian Del Priore, MD, PhD, Center Director Stephen Tsang, MD, PhD Module I, Assessing severity, progression, and prognosis of I) ABCA4 retinopathies and II) retinitis pigmentosa (RP) Marco Zarbin, MD, PhD Module II, Toxicity assessment of bovine corneal endothelial cell conditioned media following subretinal injection in pigs Lucian Del Priore, MD and Hui Cai, MD, PhD Module III, Bruch's Membrane Repair in Advanced AMD: A Regenerative Medicine Approach Rando Allikmets, PhD Module IV, Gene Therapy for Stargardt's Disease Janet Sparrow, PhD Module V, Assessing Treatment Outcomes in Pre-clinical Studies of ABCA4-related Retinal Disease, Relevance to Patient Studies Kearn Family Center for the Study of Retinal Degeneration University of California at San Francisco University of California, Berkeley, Sacramento, CA Stanford School of Medicine, Stanford, CA Loyola Marymount University, Los Angeles, CA LaVail, Matthew PhD, Center Director Matthew LaVail, PhD Module I, Neuroprotective and Gene-Based Therapies for Retinal Degenerations John Flannery, PhD Module II, Viral-Mediated Gene Therapy for Retinal Degenerations Douglas Vollrath, MD, PhD Module III, Identification of Proteins Required for Endogenous Neuroprotection and Retinal Pigment Epithelium (RPE) Phagocytosis Jacque Duncan, MD and Austin Roorda, PhD Module IV, High Resolution Retinal Imaging in Patients with Inherited Retinal Degenerations Oregon Health and Science University Research Center for the Study of Retinal Degenerations Oregon Health and Science University, Portland, OR University of Florida College of Medicine, Gainesville, FL Richard Weleber, MD, Center Director Richard Weleber, MD, Peter Francis, MD, PhD, Chris Johnson, PhD Module I, Clinical and Human Studies (Core Module), Module I Supplement: Study of Autoimmune Retinopathies Martha Neuringer, PhD, Brett Jeffrey, PhD, William Hauswirth, PhD, Betsy Ferguson, PhD, Richard Weleber, MD Module III, Nonhuman Primate Models of Retinal Disease William Hauswirth, PhD Module V, Cone Targeted Gene Therapy Paris Research Center for the Study of Retinal Degenerative Diseases Inserm, Institut de la Vision, Paris, France Jose-Alain Sahel, MD, Center Director Thierry Léveillard, PhD Module I, Molecular Signaling of Cone Rescue and Rod Differentiation Christine Petit, MD Module III, Usher I Syndrome Pathogenesis Saddek Mohand-Said, MD, PhD Module IV, Optimization and Development of Morphological and Functional Retinal Exploration Techniques of Age-related and Inherited Retinal Degeneration Cohort Follow-up and Clinical Studies PENN Large Animal Model Translational and Research Center University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA Cornell University, Ithaca, NY Gustavo Aguirre, VMD, PhD, PhD, Center Director Gregory Acland, BVSc, Gustavo Aguirre, VMD, PhD, William Beltran, VMD, PhD, Andras Komaromy, DVM, PhD Module 1, Medical Therapy Service Gustavo Aguirre, VMD, PhD, Barbara Zangerl, VMD, PhD, William Beltran, VMD., PhD Module II, Identification, Development and Molecular/Cellular Studies of New and Established Canine Retinal Degeneration Models Barbara Zangerl, VMD, PhD and Gustavo Aguirre, VMD, PhD Module III, Gene Expression/Molecular Pathways in Photoreceptor Cell Death/Survival Research Center for Macular Degeneration and Allied Retinal Diseases University of Iowa, Iowa City, IA Edwin Stone, MD, PhD, Center Director Edwin Stone, MD, PhD, Val Sheffield, MD, PhD, Terry Braun, PhD, James Folk, MD, Steve Russell, MD, Becky Johnston, Dianna Brack Module I, Large Scale Collaborative Genotype/Phenotype Correlations Val Sheffield, MD, PhD, Terry Braun, PhD, Edwin Stone, MD, PhD, Joseph Janutka, Jade East Module II, Discovery of New Retinal Disease Genes Robert Mullins, PhD, Diane Slusarski, PhD, Val Sheffield, MD, PhD, Edwin Stone, MD, PhD, Beverly Davidson, PhD, Markus Kuehn, PhD, Alisdair Philp, PhD, Marissa Olvera Module III, Gene Transfer and Animal Models Thomas Casavant, PhD, Todd Scheetz, PhD, Jian Huang, PhD, Kai Wang, PhD, Edwin Stone, MD, PhD, Val Sheffield, MD, PhD, Maureen Megonigal, PhD Module V, Regulatory Elements and Modifier Genes in Human Retinal Degeneration Research Center for the Study of Retinal Degenerative Diseases at the Institute of Ophthalmology and Moorfields Eye Hospital Institute of Ophthalmology and Moorfields Eye Hospital London, University College London, England, United Kingdom Frederick Fitzke, PhD, Center Director Frederick Fitzke, PhD, AT Moore, PhD, Alan Bird, PhD, Andrew Webster, MD, Michel Michaelides, MD, Graham Holder, PhD, Anthony Robson, MD, John Yates, PhD Module II, Imaging and Psychophysical Studies in Retinal Degenerations Shomi Bhattacharya, PhD, Christina Chakarova Module IV, Genetic Studies and Functional Genomics of Retinal Diseases Scheie Eye Institute Retinal Degeneration Center University of Pennsylvania School of Medicine, Scheie Eye Institute, Philadelphia, PA University of Florida College of Medicine, Gainesville, FL Samuel Jacobson, MD, PhD, Center Director Samuel Jacobson, MD, PhD Module I, FFB Center Grant Clinical Module Artur Cideciyan, PhD Module II, Translational Studies William Hauswirth, PhD Module III, Gene Therapy for Dominant Stargardt's Disease, GC1 LCA and CEP290 LCA Krzysztof Palczewski, PhD Module IV, Pharmacological Therapy for Retinal Degenerations Gustavo Aguirre, VMD, PhD, PhD and William Beltran, DVM, PhD Module V, Characterization of Retinal Remodeling in Canine Models of LCA/ Early Onset Retinal Degeneration Southwest Regional Center for the Study of Retinal Degenerative Diseases Retina Foundation of the Southwest, Dallas, TX University of Texas, Houston, TX University of Oklahoma, Oklahoma City, OK Robert Anderson, MD, PhD and David Birch, PhD, Center Directors David Birch, PhD, Rand Spencer MD, Dianna Wheaton, MS, Dennis Hoffman PhD Module I, Treatment Trials for Retinal Degenerative Diseases Dianna Wheaton, MS, David Birch, PhD, Stephen Daiger, PhD Module II, Southwest Eye Registry Stephen Daiger, PhD, Lori Sullivan, PhD, Sara Bowne, PhD Module V, Molecular Studies of Autosomal Forms of RP Stephen Daiger, PhD Module VI, “RetNet” Robert Anderson, MD, PhD Module VII, Biochemical Studies of the Function of the ELOVL4 Protein James McGinnis, PhD Module VIII, Vacancy Engineered Inorganic Particles and the Prevention of Retinal Degeneration Muayyad Al-Ubaidi, PhD Module IX, Role of Tyrosylprotein Sulfotransferase (TPST-1) in rod and cone associated disorders Muna Naash, PhD Module X, Delivery and Targeting of Ocular Therapeutics using Nanotechnology University of Illinois at Chicago Research Center for the Study of Retinal Degenerative Diseases University of Illinois, Eye and Ear Infirmary, Chicago, IL Gerald Fishman, MD, Center Director Gerald Fishman, MD, Kenneth Alexander, PhD, Robert Anderson, PhD, Janet Szlyk, PhD, Marty Lindeman, Martha Apushkin, PhD Module I, Clinical Investigations Gerald Fishman, MD, Edwin Stone, MD, PhD, Robert Koenekoop, MD, PhD, William Kimberling, PhD Module II, Collaborative Molecular Genetic Studies Wilmer Eye Institute Research Center for the Study of Retinal Degenerative Diseases Johns Hopkins University School of Medicine, Baltimore, MD Duke University, Durham, NC Peter Campochiaro, MD, Center Director Nicholas Katsanis, PhD Module I, Identification of Genetic Defects in Patients with AMD Jeremy Nathans, MD, PhD and Amir Rattner, PhD Module III, The Retinal Stress Response, Mueller Glia, and Stress-Induced Photoreceptor Neuroprotection Nicholas Marsh-Armstrong, PhD Module IV, Inhibiting Photoreceptor Degeneration in Transgenic Xenopus Reporter Lines Jennifer Sung, MD, Peter Campochiaro, MD, Solomon Snyder, MD Module V, Protection of Photoreceptors from Oxidative Damage by Heme Oxygenase, Bilirubin, and Biliverdin Reductase Donald Zack, MD, PhD Module VI, Rescue of Neurotrophic Factors: Identification and Molecular Characterization of Upregulated Genes Peter Campochiaro, MD Module VIII, Effect of Sustained Expression of Neurotrophic Factors and Molecular Chaperones on Retinal Degenerations W.K. Kellogg Eye Center for the Study of Retinal Degenerative Diseases University of Michigan, W.K. Kellogg Eye Center, Ann Arbor, MI University of Massachusetts Medical School University of California at San Diego John Heckenlively, MD, Center Director John Heckenlively, MD Module I, Human Clinical Studies of Retinal and Macular Degenerative Diseases Radha Ayyagari, PhD Module II, Molecular Genetic Analysis of Patients with Retinitis Pigmentosa and Macular Degeneration Hemant Khanna, PhD Module IV, Molecular Mechanisms of Pathogenesis of X-linked Retinal dystrophies Debra Thompson, PhD Module V, Therapeutic Intervention in Vitamin A Metabolism in Visual Cycle and Related Defects David Zacks, MD, PhD Module VI, Autophagy and control of photoreceptor cell death in hereditary retinal degeneration Research FacilitiesJoe Hollyfield, PhDThe Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, OH Pathophysiology Facility for the Study of Retinal Degenerative Diseases Individual GrantsCellular and Molecular Mechanisms of DiseaseWolfgang Baehr, PhD Clinical: Structure and Function StudiesMichael Gorin, MD, PhD Gene TherapyAlberto Auricchio, MD Maria Gorbatyuk, PhD Robert Molday, PhD Miguel Seabra, MD, PhD Uwe Wolfrum, PhD Jun Yang, PhD GeneticsStephen Daiger, PhD Novel Medical TherapyJohn Ash, PhD Regenerative MedicineConstance Cepko, PhD Career Development AwardsPeter Francis, MD, PhD WOMAN’S CAREER DEVELOPMENT AWARDSIsabelle Audo, MD, PhD
WYNN-GUND TRANSLATIONAL RESEARCH ACCELERATION PROGRAM AWARDSClinical StudiesBirch, David PhD GeneticsStephen Daiger, PhD Gene TherapyHauswirth, William, PhD Novel Medical TherapiesCraig Beeson, PhD
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- 09/11/10 - St. Louis - St. Louis Vision Seminar
- 09/11/10 - Boston - Boston VisionWalk Kick Off
- 09/11/10 - Charlotte - Charlotte VisionWalk Kick Off Luncheon
- 09/11/10 - Tampa - Tampa Bay VisionWalk Kick Off Party
- 09/13/10 - Laytonsville - DC Swing for Sight Tournament






